Paid Diploma / Master's Thesis - Influence of the material moisture on a continuous pharmaceutical manufacturing process - Austria Jobs Opening

October 1, 2024

Research Center Pharmaceutical Engineering GmbH

Graz

OTHER

Paid Diploma / Master's Thesis - Influence of the material moisture on a continuous pharmaceutical manufacturing process

Paid Diploma / Master's Thesis
Influence of the material moisture on a continuous pharmaceutical manufacturing process
Ref.No DA178

To dedicated students of Chemical Engineering, Pharmaceutical Engineering, Pharmacy or related studies.

Objective
In the pharmaceutical industry, a common method for a continuous downstream process of an active pharmaceutical ingredient (API) involves blending the API, either as a powder or liquid, with excipients, followed by hot melt extrusion (HME) of the mixture. The resulting extrudates are then pelletized, mixed with additional excipients, and finally compressed into tablets.
This diploma/master’s thesis will investigate the impact of moisture on the pelletability and tabletability, the material is exposed during this manufacturing process. Therefore, the raw material, the extrudates, and the pellets will be exposed to various levels of moisture and characterized afterwards regarding their quality for pelletability and tabletability.

Withing the framework of this diploma / master’s thesis we offer the following:

Extensive participation in a top-level and industrially relevant research project in an international environment
Supervised training in the task
Assistance of experienced staff with the implementation of innovative ideas
Access to highly modern infrastructure on campus of Graz University of Technology
Assistance with the publication of results

Financing:

Compensation on the basis of a service contract

If you are interested in writing your thesis at the interface between university research and industry/ business and to contribute to the optimization of product and process development in the pharmaceutical industry, please apply directly via our website.

We regret to inform you that this job opportunity is no longer available