Introduction
The University of Lausanne is a higher teaching and research institution located right by the Geneva lake overlooking the Alps in Switzerland. It is composed of seven faculties, including a Faculty of Biology and Medicine training biologists/medical doctors and performing internationally recognized research projects in the fields of fundamental biology and biomedical/clinical research. Scientists/students working on our campus have access to exceptional state-of-the-art core facilities (ex: imaging, genomic, bioinformatic) and training in a highly international environment.
Presentation
The Department of Fundamental Microbiology (https://www.unil.ch/dmf/en/home.html) offers a Graduate Assistant position in Bacterial genetics.
Job information
Expected start date : 01.01.2025 (flexible)
Contract length : 1 year, renewable up to 5 years.
Activity rate : 85%
Workplace : University of Lausanne
Your responsibilities
The Collier lab has an open position to study the roles of DNA methylation in the Caulobacter crescentus Alphaproteobacterium. DNA methylation can impact gene expression through epigenetic mechanisms of regulation, but also the capacity of bacteria to exchange genes (including antibiotic resistances) through horizontal gene transfers or to resist to phage infections. Caulobacter crescentus is one of the best model systems to study such biological processes, as it is easy to cultivate and modify genetically, while it carries five different DNA methyltransferases (DNA MTases) methylating its genome. The goal of the advertised project will be to characterize the role of two of these DNA MTases, combining genetic, genomic, phenotypic and fluorescence microscopy approaches. Preliminary results from our team indicate that one of these may play a role in controlling DNA/plasmid entry into cells, while the other may be connected with cell division. We are then looking for a highly motivated candidate to join our research group.
At least 60% of the activity will be dedicated to personal research. The other 25% will be for the research of the group and to contribute to the teaching of practical courses for Bachelor students.
Your qualifications
Applicants must have a Master of Science in Biological sciences and a strong motivation for fundamental research and bacterial genetics. Previous experience in microbiology, genetic engineering, genomic and/or bioinformatics are a plus. Applicants must speak/write English fluently as this is the everyday working language in our department.
What the position offers you
We offer a stimulating position in a highly international environment with an outstanding doctoral school (https://www.unil.ch/ecoledoctoralefbm/en/home.html).
Our lab is located on the University of Lausanne campus, with immediate access to the lake and a rich cultural life. Please visit our website for more information on our group, research interests and publications: https://wp.unil.ch/collierlab/.
Contact for further information
Prof. Justine COLLIER: justine.collier@unil.ch
Your application
Application deadline: 20.10.2024 (earlier applications are more than welcome).
Please include your full application in English as a single PDF, including: (1) a motivation letter explaining why this project interests you, (2) a complete CV, (3) a short description of your previous research experience (Master project, internships in labs…), (4) the name/email/website of 2-3 references, (5) your Master thesis (if you are allowed to share it).
Only applications through this website will be considered. We thank you for your understanding.
Additional information
UNIL is committed to equal opportunities and diversity.
www.unil.ch/egalite
UNIL supports early career researchers.
www.unil.ch/graduatecampus